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Science and Efficacy

Thousands of clinical studies have been published on the science and efficacy behind the ingredients in EnzymePlus


The enzymes in EnzymePlus. Blocks the messengers of inflammation.

Natural enzymes extracted from the stem of pineapples which has powerful anti-inflammatory effects. Is known to block the messengers of inflammation (cytokines) to help prevent the inflammatory response from spreading to healthy tissues. [1-5] 

Arginine & Citrulline

Increases Blood Flow and Tissue Perfusion.

Protects the cardiovascular system and regulates the immune system.

Increases nitric oxide which dilates blood vessels and increases circulation and tissue perfusion [6-8]. This translates to better oxygen and nutrient supply to tissues and more efficient clearing of metabolic wastes such as ammonia and lactic acid [9]. 

Nitric oxide has also been shown to reduce white blood cell adhesion to the vascular lining. This restores an overactive immune system to its healthy state and protects the heart from oxidative stress[10,11].  Long term use of arginine has also shown to protect the vascular lining and reverse arterial plaque formation [12]. 

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Nobel Prize Winning Science

Dr. Louis Ignarro - winner of the 1998 Nobel Prize in Medicine discusses his discovery of nitric oxide and the role of arginine and citrulline in preventing blood clots and cardiovascular disease.


Protects the intestinal lining and fuels the immune system.

An essential amino acid for the immune system and digestive system. Glutamine is used rapidly as a fuel source by the immune system. It's been proposed that illness and infection caused by athletic over training may be the result of glutamine deficiency as glutamine has been shown in clinical studies to significantly reduce infection rates in extreme endurance athletes [13-15]. 


Helps reduce oxidative stress and free radicals.

Vitamin C and organic fruit extracts are powerful antioxidants which help to reduce oxidative stress and free radical tissue damage. They also double as natural flavouring and colouring, avoiding unnecessary fillers and artificial ingredients. 

[1] J Pain Res. 2016;9:941-961. [2] Clin Immunol. 2008;126(3):345-52. [3] Clin Immunol. 2005;116(2):135-42. [4] J Assoc Physicians India. 2001;49:617-21. [5]  Phytomedicine. 2002;9(8):681-6.[6]  Int J Cardiol. 2002;86(2-3):317-23. [7]  J Clin Invest. 1996;97(8):1989-94. [8]  Exp Physiol. 2017;102(12):1661-1671 [9]  Br J Sports Med. 2002;36(4):282-9. [10] Atherosclerosis. 1997;129(2):261-9. [11] Arterioscler Thromb Vasc Biol. 1997;17(12):3557-64. [12]  Mol Cell Biochem. 2005;269(1-2):1-11.  [13] Eur J Appl Physiol Occup Physiol. 1996;73(5):488-90. [14]  Nutrition. 1997;13(7-8):738-42. [15]  Cell Stress Chaperones. 2015;20(1):85-93. 

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